Tim peneliti FKUI bersama tim Dinas Kesehatan DKI Jakarta mengungkap kematian 381 pasien dari 4.052 pasien terkonfirmasi positif COVID-19. Pasien-pasien tersebut berasal dari fasilitas kesehatan di DKI Jakarta. Penelitian ini telah dipublikasi di jurnal Acta Medica Indonesiana, sebuah jurnal bertaraf internasional Q3. Melalui penelitian ini, terungkap bahwa usia tua, pneumonia, sesak napas, dan hipertensi merupakan faktor-faktor prediktor terjadinya kematian pada pasien terkonfirmasi COVID-19.
Tim peneliti FKUI terdiri atas Dr. dr. Anna Rozaliyani, Sp.P, M.Biomed; dr. Diah Handayani, Sp.P(K); dan dr. Findra Setianingrum bekerja sama dengan dr. Ary I. Savitri dan dr. Titania N. Shelly dari Siena Clinical – Academic Research Organization; dr. Vini Ratnasari dari RSUD Pasar Rebo; dr. Romala Kuswindarti dari RSUD Ciracas; serta dr. Ngabila Salama, dr. Dwi Oktavia, dan dr. Widyastuti, MKM dari Dinas Kesehatan Provinsi DKI Jakarta.
Hasil penelitian menunjukkan bahwa rata-rata usia pasien COVID-19 yang meninggal dunia adalah 58,2 tahun. Risiko kematian meningkat mulai usia 50 tahun ke atas dengan perbedaan signifikan dibandingkan usia di bawahnya. Dari 41,1% pasien COVID-19 dengan pneumonia, sebanyak 81,6% pasien meninggal. Batuk, demam, dan sesak napas merupakan gejala-gejala yang banyak dijumpai pada pasien-pasien ini. Walaupun begitu, gejala lain seperti malaise, nyeri kepala, nyeri tenggorokan, pilek, mual muntah, nyeri perut, dan diare tidak dapat diabaikan.
Peningkatan risiko kematian pasien COVID-19 di usia tua diduga karena sistem imun tubuh yang menurun. Akibatnya, mereka menjadi lebih rentan untuk mengalami kondisi serius dan respons pengobatan yang tidak maksimal. Pasien dengan pneumonia dan sesak napas juga sangat mungkin mencapai luaran buruk karena peluang pasien-pasien ini untuk jatuh ke dalam kondisi acute respiratory distress syndrome (ARDS) meningkat.
Penelitian ini juga menyatakan bahwa hipertensi meningkatkan risiko kematian pasien COVID-19 sebesar dua kali lipat. Keberadaan penyakit-penyakit kardiovaskular termasuk hipertensi ternyata berkontribusi terhadap kejadian pneumonia dan gejala fatal COVID-19 lainnya. Hal ini patut menjadi perhatian mengingat hipertensi merupakan komorbiditas terbanyak yang ditemukan pada pasien COVID-19.
Dekan Fakultas Kedokteran Universitas Indonesia, Prof. Dr. dr. Ari Fahrial Syam, Sp.PD-KGEH, MMB menyambut baik studi ini dan menyampaikan apresiasinya kepada para peneliti. “Hasil penelitian ini diharapkan mampu memberikan informasi, baik kepada masyarakat maupun klinisi mengenai faktor-faktor yang memengaruhi risiko kematian pasien COVID-19, serta mendorong seluruh komponen masyarakat untuk selalu bersikap waspada dan menerapkan upaya pencegahan apalagi melihat angka kematian akibat COVID-19 di Indonesia terbilang tinggi jika dibandingkan dunia,” tutur Prof. Ari
Penelitian dapat diakses dan diunduh di http://www.actamedindones.org/index.php/ijim/article/view/1525
#bersatumelawancovid19
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Humas FKUI
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Exceeding really helpful doses considerably will increase the risk of unfavorable side effects. Correct food plan, training, and cycle support are vital for getting essentially the most out of an Anavar cycle safely and successfully. One of the difficulties in testing for anabolic steroids, as opposed to leisure medicine, is that hormones like testosterone and DHT are discovered naturally in the body. Effective performance drug testing, due to this fact, wants to have the flexibility to differentiate between the traditional presence of steroid hormones and people who exist because of exogenous steroid use. Whereas this could be relatively easy to detect in females who have naturally very low levels of testosterone, in male users, it must be undertaken more rigorously to keep away from false positives. What we now have to recollect in phrases of females using anabolic steroids is that you’re introducing male androgen hormones into your physique at ranges much greater than would ever be produced naturally.
Anavar retains the body in an anabolic state, so that you lose fat and hold the muscle you’ve gained from bulking cycles. Anavar will provide you with extra endurance and sooner recovery, translating to tougher, extra environment friendly cardio and exercise periods. To understand the potential results of Anavar on testosterone ranges, you will want to have a basic understanding of the hormonal system in the physique. Testosterone is a hormone that is primarily produced in the testicles in males and in smaller amounts in the ovaries in females. It plays a vital function within the growth of secondary sexual characteristics, corresponding to muscle mass, bone density, and aggression.
You bulk as a lot as placed on muscle mass after which minimize to do away with the fats and reveal the muscle beneath. It is frequent practice to stack Anavar with numerous different anabolic steroids, such as the sturdy fat burner Winstrol, Equipoise, Masteron, or Primobolan. As A End Result Of bodybuilding levels of Oxandrolone lead to a somewhat high suppression of testosterone, it is all the time recommended that males stack Anavar with Testosterone when using this steroid. This is due to the truth that bodybuilding-relevant doses of Oxandrolone induce a comparatively substantial reduction of testosterone. When the body is placed in survival mode, stress hormones rise, inflicting the body to enter shutdown mode.
So, a first-time consumer of EQ would wish to judge its influence on appetite. Clearly, throughout a slicing cycle, you don’t need a huge enhance in appetite, and if that’s so, you need to weigh up the professionals and cons of utilizing this explicit steroid throughout cutting cycles. It is usually used only firstly of a slicing cycle, so the urge for food improve could not negatively influence your final outcomes. This aspect effect, male pattern baldness, is extremely genetically determined.
Testosteronology is extra specific than Endocrinology, which offers with all hormones in women and men. And it is totally different from Urology, a surgical specialty that does not focus on the common medical aspects of how androgens effect males. These days you should purchase legal steroid options online, with producers claiming to recreate the results of anabolic steroids; however with little to no unwanted effects. We don’t believe such supplements are as powerful as actual anavar, nonetheless they won’t pose the identical harmful unwanted side effects as oxandrolone. A noteworthy aspect effect with Anavar is a modest decline in endogenous testosterone production. Drugs similar to finasteride can be used to significantly scale back DHT ranges in the physique, reducing hair loss. However, this will likely result in decreased muscle gains, as DHT is a really anabolic hormone.
When testosterone ranges are elevated, as they’re during a Check cycle, it could enhance the body’s capacity to build muscle extra effectively. Trenbolone, on the opposite hand, is understood for being a potent anabolic steroid with five times the anabolic energy of testosterone. This means Tren can promote muscle growth at a a lot quicker rate than testosterone alone. Like other anabolic steroids, Oxandrolone can suppress natural testosterone production throughout a cycle. For this cause, Submit Cycle Therapy is recommended to help restore regular testosterone ranges after use.
I began with little or no and all the time put 110% into the fitness center to get to where I am now. From anabolic steroids to SARMs to peptides and ancillary medication, I’ve carried out it sooner or later in my life, and I can relate. Nevertheless, with extra advanced detection techniques, any steroid testing is undertaken by competitions and authorities with the budget to ensure in-depth exams will pick up metabolites. Can there be a extra obvious signal of feminine steroid use than the growth of hair on the face and body? People will discover this quickly regardless of it starting slowly (depending on which steroid, your dose, and how long you use it).
Tren will ship super lean muscle and energy gains with out water retention and boosting nutrient effectivity. As a stimulant, Clen comes with some different side effects than you’ll typically see with actual anabolic steroids. A 2-week Clenbuterol cycle is the recommended maximum, with at least that very same size of time in between without Clen being used. Most customers often pyramid the dosage, however everyone will expertise completely different side effects.
Post-cycle, they can anticipate enhanced muscle definition, increased energy, and lowered body fat, supplied their diet and train are aligned with these goals. Anavar is a stronger anabolic steroid, but it also has extra potential side effects. TRT is a more pure approach to boost testosterone levels, but it may not be as efficient for some people.
Many other steroids can truly cause joint problems, particularly winstrol – but deca durabolin has the reverse effect. Nevertheless, Anavar won’t increase your testosterone levels as much as dianabol (at the beginning of your cycle), nor will it shut you down as much as deca (after your cycle). Extra critical unwanted effects of introducing synthetic testosterone into your physique embody liver harm, enlarged prostate, and higher pink blood cell count which is a predictor of coronary heart illness.
If you’re going to run a Tbol cycle, check out my full Oral Turinabol cycle information. Winstrol will suppress your testosterone so much, so you’ll want exogenous testosterone in your cycle. There are not any estrogenic results, and androgenic effects are normally delicate. It’s a particularly efficient slicing compound that may ship that highly fascinating onerous, dry look and is especially valuable when you’re already lean and want more excessive outcomes. If you’re going to run a Winstrol cycle, try my complete Winstrol (Stanozolol) cycle guide. Stanozolol is a synthetic anabolic steroid, which is a derivative of dihydrotestosterone (DHT).
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Whereas Anavar is much less likely to cause extreme virilization compared to more androgenic steroids, the risk nonetheless exists, especially at greater doses or with prolonged use. Even though Oxandrolone, also referred to as Anavar, is a popular selection amongst female bodybuilders for its mild results in comparability with other steroids, prioritizing security is vital. Safety ought to at all times be the primary concern, even when you’re aiming for improved look or performance. So, it’s best to prioritize security and persist with the recommended doses for a more practical and safer experience. While both men and women naturally produce testosterone, girls’s levels of this hormone are significantly lower than males’s.
Equally, ladies don’t want to fret about masculinization occurring on Anvarol, which we see occur on high doses of Anavar at our clinic. This often includes clitoral enlargement, irregular durations, a deepened voice, and hair development on the body. Anavar, nevertheless, does have to be cycled, with our patients typically experiencing low testosterone ranges post-cycle (typically taking a quantity of weeks to recover). Anvarol is FDA-approved and secure for men and women to take all 12 months, as it doesn’t damage the HPTA (hypothalamic pituitary testicular axis) and suppresses natural testosterone ranges. HGH-x2 is another powerful fat-burning compound that complements Anvarol’s results when cutting because of its lipolytic properties. However, this effect may be harmful if abused since rising anabolic exercise with out first taking good care of important organs is not really helpful always due to its potential side effects.
Enhancing strength and endurance is one other noteworthy aspect of Anavar’s cutting-oriented benefits. Enhancing users’ bodily efficiency empowers them to push via their exercises with heightened depth and focus. This can result in continuous progress as the body adapts to more onerous calls for and escalating challenges. Moreover, a noticeable reduction in physique fats can be obvious, due to the improved metabolism the substance offers. It’s very important to proceed monitoring food regimen and exercise routines all through this period for the most effective results. By sustaining self-discipline and willpower, male users can capitalize on the spectacular outcomes Anavar provides. We love our prospects (both present and future), and the products anabolic steroids online we offer are based mostly mainly on requests from people such as you.
Hardcore Clen customers who threat using higher doses are these most capable of tolerate the tough unwanted aspect effects. 100mcg isn’t unheard of, and some customers have taken 120mcg and seen pretty unbearable unwanted effects (not recommended). But these advantages will solely be worthwhile chasing after if your diet works out and got in form naturally for a while. If you’re a higher-weight person, Clenbuterol isn’t what you should consider using. Clen has high bioavailability at up to 98% and avoids first-pass metabolism11.
When Im not in the gym or spending time away from my household i typically think about what recommendation would help others achieve theirs targets just like these inspired mine. This helps with improved oxygen supply, resulting in elevated energy and endurance. Users can also expect average quantities of muscle growth and fat burning when taking Anavar. Many anabolic steroids will scale back subcutaneous fats, but enhance visceral fats (3). Consequently, steroid-users can typically be seen trying bloated or fat (despite being very lean).
However, it is important to not overdo it, as this could enhance the risk of injury or burnout. Nutrition must be tailored to assist targets, sometimes involving a high-protein diet with enough healthy fat and complex carbohydrates. For those using Anavar for cutting, a average calorie deficit can be implemented to promote fat loss whereas the compound helps preserve muscle mass.
From my very own personal expertise, girls ought to tread with caution before taking any type of anabolic steroid. This makes good senses, throughout a slicing cycle most ladies cut back on calories and carbs which can scale back power ranges. Due to Anavars low androgenic score, it has been popular within the treatment of involuntary weight reduction. It is utilized in to deal with patients suffering from HIV/AIDS 1 and has also proven constructive advantages in the remedy of these suffering from osteoporosis. Utilizing the drug for a really long time greatly will increase the possibilities of masculinization with high doses and long cycles. These results enhance nutrient delivery, energy constructing, and restoration, leading to maximum positive aspects. From a scientific point of view, this is because they will improve the manufacturing of ATP, elevate testosterone ranges, and velocity up protein synthesis.
It’s critical, though, that its use is supported by sound information and warning concerning the dosages and cycles. This means, female bodybuilders can genuinely reap the rewards of their labor-intensive coaching with out incurring pointless dangers. It is extraordinarily important to stay to the proper dosage of any supplement or steroid for it to soundly work on the physique. At the top of the day, you do not want to do anything that may cause potential damage to the body. As for Anavar, the really helpful every day dosage for an adult is 2.5 mg to twenty mg administered in 2 to 4 separate doses.
The adjustments in physique composition, nonetheless, might be much less pronounced as compared to the transformations seen during a extra prolonged cycle. When in contrast with other anabolic steroids, there are heaps of benefits that Anavar for girls has, and which makes it extremely popular amongst the budding female bodybuilders. Here is a short take a look at a number of the benefits you presumably can count on to have as a lady wanting ahead to tapping into the magic of steroids for attaining health objectives. Understanding each the potential advantages and risks allows for knowledgeable decision-making.
As A End Result Of of its efficiency in safely addressing health considerations, the FDA has given a green sign to this steroid for pharmaceutical use solely, and is banned for bodybuilding use. However many fitness enthusiasts around the globe buy Anavar from the black marketplace for weight loss and slicing assist. In conclusion, while Anavar could provide some advantages for women, its potential for harmful side effects and legal implications make it a dangerous choice. Anvarol by CrazyBulk supplies a secure and legal alternative that can help women obtain their health targets without compromising their well being or breaking the legislation. Sure, Anavar can be used on its own, however it may not produce the most effective results when it comes to muscle development and fats loss. Stacking Anavar with different steroids might help to enhance muscle development and enhance fat loss potential. In current years, Anavar has turn out to be increasingly popular amongst girls who wish to enhance their physique and athletic performance.
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Implementing post-cycle remedy (PCT) is helpful, as Anavar will lower endogenous testosterone production. This could additionally be much less severe in comparability with an Anadrol-only cycle; nevertheless, we’ve observed hypogonadism transpiring from Anavar-only cycles. Without PCT, testosterone deficiency could final for several weeks or months. The main concern we’ve with clenbuterol is cardiotoxicity, with it potentially inflicting tachycardia. We have additionally observed clenbuterol inflicting insomnia, anxiety, depression, and nervousness in customers. It is banned by the FDA and several other sporting federations as a result of it being a growth-promoting compound and its opposed effects.
I ordered from an outfit based in the UK and recieved supply four days later. As with most drugs, there will always be unwanted effects, particularly whenever you use them in excess. The greatest drawbacks of Clenbuterol would have to be that the unwanted side effects are unbearable and that it’s an unlawful compound. When it comes to medicine that influence Beta Receptors, they’ll all have similar results. The downside with advising on banned substances is that there are restricted scientific studies on the doses we use these substances.
Generally, anabolic steroids are hepatotoxic, as indicated by our liver operate exams. Nevertheless, Andriol doesn’t trigger any notable hepatic strain, based mostly on long-term research. A 10-year examine of males using Andriol observed no notable improve in alanine transaminase (ALT) and aspartate aminotransferase (AST) levels. An Anavar-only cycle is often practiced by novices and intermediates all through a slicing phase. An Anavar-only cycle can improve fat burning whereas adding moderate quantities of muscle mass. It is crucial for women contemplating Oxandrolone utilization to concentrate on the potential virilizing effects.
High blood strain is doubtless one of the most typical medical circumstances in the world, and it may possibly result in numerous critical well being problems. When blood stress is just too high, it locations additional strain on the center and blood vessels, which might finally lead to heart attacks, strokes, and kidney damage. You should talk to your doctor should you experience nausea whereas taking Anavar. As a result, Anavar can help enhance bones’ strength and density, making them much less likely to break. This may be extremely beneficial for athletes and older adults who are in danger for fractures.
This helps burn off saved fats as the physique is continually at a heightened metabolic price, even at relaxation. Then consider the slicing stack if you’re looking to combine Anvarol with other comparable nice slicing supplements. Moreover, Anavar also can help to increase muscle mass, which might further shield bones from injuries.
Determining the appropriate dosage of Anavar is essential for optimizing results and minimizing potential side effects. The following desk provides dosage pointers based mostly on consumer expertise level, serving to people make informed choices about their Anavar utilization. Women who use Anavar typically report increased muscle tone, improved strength, and a extra outlined physique. Oxandrolone, also called Anavar, may be stacked with Winstrol to have the ability to maximize the benefits and effects of both steroids within the body. For starters, this stack can provide a a lot larger increase in lean muscle mass improve, as properly in energy levels, efficiency, and energy. In addition, Oxandrolone does not aromatize into estrogen, which implies it doesn’t cause water retention. Moreover, stacking Oxandrolone with Winstrol can present many other benefits such as a rise in fats loss that is extra pronounced when you combine the two steroids in this stack.
This attribute allows it to bypass the liver and turn into totally lively, leading to minimal hepatotoxicity. Compared to other steroids, Anavar is metabolized primarily by the kidneys, making it a beautiful option for bodybuilders seeking to keep away from liver injury. In the realm of bodybuilding, I am constantly looking out for ways to optimize my workouts and obtain superior outcomes. One specific substance that has captivated my consideration is Anavar, also called Oxandrolone.
Nevertheless, visceral fats is positioned nearer the interior organs and cannot be seen, although high ranges can push out the abdomen, inflicting a bloated or protruding look. Also, users are advised to get their ALT and AST levels checked pre-cycle to make sure they’re in a normal range. While my results have been promising, it’s all the time necessary to notice that individual responses can range. Anvarol brings about a very watered-down version of the advantages loved by anyone taking Anavar. If you desire a pure, over-the-counter, authorized, moral drive multiplier to work slightly like Anavar, though far much less potently, you’ll do well taking a glance at Anvarol by CrazyBulk. Even reasonable PEDs like Anavar convey too many disagreeable side effects and moral considerations to make them a tenably good idea. Anavar utilization can result in zits as a result of elevated pores and skin oiliness, as properly as other pores and skin changes.
Many individuals prefer purchasing it on-line from reliable sources, even and not using a prescription. On the opposite hand, procuring Anavar from a local pharmacy requires a valid prescription. Many athletes and individuals striving for fats loss and muscle gain opt to order Anavar online to avoid extra bills. Imagine witnessing a remarkable transformation – a testament to the facility of willpower and the impression of a well-designed fitness regimen. Anavar, an anabolic steroid extensively used by bodybuilders and athletes, has garnered attention for its potential to produce significant bodily adjustments.
There are some animal research, and lots of of people have used these substances. Clenbuterol will solely be used to decrease fat mass and will not increase muscle mass. Pure options and life-style changes are both viable and effective methods for attaining weight-related goals. This strategy, coupled with a balanced food regimen and regular exercise, can lead to sustainable and healthy weight administration. The impression of steroids on weight acquire can differ tremendously and is influenced by quite a few components, corresponding to the kind of steroid, the dosage, particular person metabolism, and dietary habits. A brief use of steroids for every week may not lead to vital weight achieve. Anavar, also referred to as Oxandrolone, has gained recognition in the fitness group for its potential to reinforce bodily performance and enhance physique composition.
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